Research articles published from the ERA Chair and collaborators

Two research articles from the ERA Chair and collaborators have been published that exploited adaptive laboratory evolution (ALE) for the first time to improve phenotypes of wild-type Clostridium autoethanogenum. First article led by the ERA Chair team and collaborators from Australia, the USA, and Switzerland utilised ALE to engineer superior strains with faster growth, no need for yeast extract, and robust bioreactor performance on CO-containing gases. Second article from the ERA Chair and collaborators from Australia and the USA developed faster growing strains on CO₂+H₂ that showed widespread proteome and intracellular metabolome changes. Both works suggest novel targets for metabolic engineering of cell factories.